Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
Peer-reviewed industrial hemp research by Erin A. McClure; Leah Hamilton; Gillian L. Schauer; Theresa E. Matson; Gwen T. Lapham published in Addictive Behaviors (2023).
A correlation between mental illness and systemic rheumatoid arthritis (RA) has been observed in several prior investigations. However, little is known about the causative relationship between them. The present study aimed to systematically investigate the potential association between genetically determined mental illness and RA. Two-sample bidirectional Mendelian randomization (MR) analysis was performed using publicly released genome-wide association studies (GWAS). We selected independent ge
The Cochrane IBD Group presented a symposium at Digestive Diseases Week 2018 entitled “Alternative and Complementary Approaches for the Treatment of IBD: Evidence from Cochrane Reviews.” This article summarizes the data presented at this symposium.
Importance Electronic nicotine delivery systems (ENDS) were created to vape nicotine e-liquids; however, social media demonstrates increased ENDS modifications to vape cannabis. Analysis of social media content helps with understanding ENDS modifications for cannabis use, overlapping markets for ENDS and cannabis, and the need for additional regulation. Objective To analyze online videos for use, modification, and marketing of ENDS to vape cannabis. Design, Setting, and Participants In this qual
Peer-reviewed industrial hemp research by Daisy Hassani; Lorraine Flick; Hareena Sangha; Lily A. Brown; Uduak U. Andy; Lily A. Arya published in International Urogynecology Journal (2021).
Microglia, as the immune guardians of the central nervous system (CNS), have the ability to maintain neural homeostasis, respond to environmental changes, and remodel the synaptic landscape. However, persistent microglial activation can lead to chronic neuroinflammation, which can alter neuronal signaling pathways, resulting in accelerated cognitive decline. Phosphoinositol 3-kinase (PI3K) has emerged as a critical driver, connecting inflammation to neurodegeneration, serving as the nexus of num
Abstract Background As the use of herbal therapies alongside conventional medications continues to rise, understanding the complexities of these interactions becomes essential for ensuring patient safety and optimizing therapeutic outcomes. Main body Herbal remedies, sometimes referred to as phytotherapy or herbalism, use plants and plant extracts for medicinal purposes. Various plant parts, such as leaves, roots, flowers, and seeds, are used in herbal medicines to cure illnesses and enhance hea
This first longitudinal cohort study examining the mediational relationship between cannabis use, anxiety/depressive symptoms and PE, shows that there is a bidirectional relationship between cannabis use, anxiety/depressive symptoms and PE. However, the contribution of anxiety/depressive symptoms as a mediator was greater than that of cannabis.
Peer-reviewed industrial hemp research by Monica Aas; Lucia Sideli; Christian Franceschini; Luis Alameda; Giulia Trotta; Gianluca Lo Coco; Alessandro Musetti; Adriano Schimmenti published in Psychiatry Research (2023).
Distressing low sexual desire, termed Hypoactive Sexual Desire Disorder (HSDD), affects approximately 10% of women and 8% of men. In women, the 'top-down' theory of HSDD describes hyperactivity in higher-level cognitive brain regions, suppressing lower-level emotional/sexual brain areas. However, it is unknown how this neurofunctional disturbance compares to HSDD in men. To investigate this, we employed task-based functional MRI in 32 women and 32 men with HSDD to measure sexual-brain processing
Peer-reviewed industrial hemp research by Wura Jacobs; Ashley L. Merianos; Patrick D. Quinn; Jessica L. Barrington‐Trimis; Adam M. Leventhal published in BMC Public Health (2023).
Nonpunitive policies and training on cannabis use are critical steps for supporting providers to counsel patients who use cannabis during pregnancy, alongside a harm reduction approach that acknowledges the broader socio-structural contexts and barriers facing patients who disclose use.
UCM1341, by enhancing endocannabinoid and melatoninergic signalling, benefits neuroprotection and stimulates inflammation resolution pathways. Our findings provide an encouraging prospect of therapeutically targeting endocannabinoid and melatoninergic systems in inflammatory demyelinating states in the CNS.
Peer-reviewed industrial hemp research by Miaomiao Li; Dan Wang; Wenpeng Bi; Zheng-er Jiang; Ri-Long Piao; Hai-Ling Yu published in Journal of Pharmacology and Experimental Therapeutics (2019).
Abstract Major depressive disorder (MDD) is associated with T cell activation (Maes et al. 1990-1993), but no studies have examined the combined effects of T cell activation and deficits in T regulatory (Treg) cells on the severity of acute phase MDD. Using flow cytometry, we determined the percentage and median fluorescence intensity of CD69, CD71, CD40L, and HLADR-bearing CD3+, CD4+, and CD8+ cells, and cannabinoid type 1 receptor (CB1), CD152 and GARP-bearing CD25+FoxP3 T regulatory (Treg) ce
Radiation for medical use is a well-established therapeutic method with an excellent prognosis rate for various cancer treatments. Unfortunately, a high dose of radiation therapy comes with its own share of side effects, causing radiation-induced non-specific cellular toxicity; consequently, a large percentage of treated patients suffer from chronic effects during the treatment and even after the post-treatment. Accumulating data evidenced that radiation exposure to the brain can alter the diver
Peer-reviewed industrial hemp research by Tabea Schoeler; Jessie R. Baldwin; Ellen Martin; Wikus Barkhuizen; Jean‐Baptiste Pingault published in Nature Mental Health (2024).
DERR1-10.2196/37153.
DOI 10.17605/OSF.IO/5JTAQ.
In the future, AI chatbots will become more intelligent and personalized, providing users with precise, efficient, and convenient psychological counseling services. The results of this research provide valuable technical insights for further improving AI-supported psychological counseling, contributing positively to the application and development of AI technology.
Psychoneuroendocrinoimmunology is the area of study of the intimate relationship between immune, physical, emotional, and psychological aspects. This new way of studying the human body and its diseases was initiated in the last century's first decades. However, the molecules that participate in the communication between the immune, endocrine, and neurological systems are still being discovered. This paper aims to describe the development of psychoneuroendocrinoimmunology, its scopes, limitations
There is increasing evidence that hypercholesterolemia has an intrauterine developmental origin. However, the pathogenesis of fetal-originated is still lacking in a theoretical system, which makes its clinical early prevention and treatment difficult. It has been found that an adverse environment during pregnancy (e.g., xenobiotic exposure) may lead to changes in fetal blood cholesterol levels through changing maternal cholesterol metabolic function and/or placental cholesterol transport functio
This study showed that the efficacy of CUR on IBS-C was possibly by modulating the microbiota and lowering the serum levels of HT, SP, and VIP.
Peer-reviewed industrial hemp research by Marion McNabb; Katherine A. Durante; Sarah Trocchio; David J. Ritter; Randal Maccaffrie; Ann Brum; Stephen Mandile; Steven R. White published in Clinical Therapeutics (2023).
Neuroimaging studies of psychedelics have advanced our understanding of hierarchical brain organisation and the mechanisms underlying their subjective and therapeutic effects. The primary mechanism of action of classic psychedelics is binding to serotonergic 5HT2A receptors. Agonist activity at these receptors leads to neuromodulatory changes in synaptic efficacy that can have a profound effect on hierarchical message passing in the brain. Here, we review the cognitive and neuroimaging evidence