Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
Our study elucidates that acupuncture at Neiguan modulates anxiety by activating or deactivating these brain anxiety-related regions and provides potential explanations for the application of PC6 acupuncture in mental diseases.
ClinicalTrials.gov Identifier: NCT02849587.
Peer-reviewed industrial hemp research by Aníbal Sánchez-De La Torre; Tania Aguado; Alba Huerga-Gómez; Silvia Santamaría Santamaría; Antonietta Gentile; Juan Carlos Chara; Carlos Matute; Krisztina Monory; Susana Mato; Manuel Guzmán published in Cell Death and Disease (2022).
Peer-reviewed industrial hemp research by Mackenzie Taylor; Janna Cousijn; Francesca M. Filbey published in Current Addiction Reports (2019).
ISRCTN Registry ISRCTN11086185; http://www.isrctn.com/ISRCTN11086185.
Peer-reviewed industrial hemp research by Muanpetch Rachayon; Ketsupar Jirakran; Pimpayao Sodsai; Atapol Sughondhabirom; Michaël Maes published in Scientific Reports (2024).
Peer-reviewed industrial hemp research by Ana Martín‐Sánchez; Héctor González‐Pardo; Laia Alegre-Zurano; Adriana Castro‐Zavala; Isabel López-Taboada; Olga Valverde; Nélida M. Conejo published in Progress in Neuro-Psychopharmacology and Biological Psychiatry (2021).
Microglia-mediated neuroinflammation is widely perceived as a contributor to numerous neurological diseases and mental disorders including depression. Discs large homolog 1 (Dlg1), an adaptor protein, regulates cell polarization and the function of K<sup>+</sup> channels, which are reported to regulate the activation of microglia. However, little is known about the role of Dlg1 in microglia and the maintenance of central nervous system homeostasis. In this study, we found that Dlg1 knockdown sup
Peer-reviewed industrial hemp research by Xinyu Li; Binjie Chen; Dianjun Zhang; Siman Wang; Yuliang Feng; Xiafang Wu; Lulu Cui; Ming Ji; Wenliang Gong; Alexei Verkhratsky published in Molecular Psychiatry (2023).
Recent data show that young people, mainly due to the pressure of some risk factors or due to disrupted interpersonal relationships, utilise greater reward value and display greater sensitivity to the reinforcing properties of "pleasurable stimuli", specifically in those situations in which an enhanced dopamine release is present. Alcoholic beverages, foods rich in sugar and fat, and illicit drug use are pleasurable feelings associated with rewards. Research shows that there is a link between su
Peer-reviewed industrial hemp research by Albert Stuart Reece; Gary Kenneth Hulse published in BMC Public Health (2020).
Food, energy, and water (FEW) sectors are inextricably linked, making one sector vulnerable to disruptions in another. Interactions between FEW systems, viral pandemics, and human health have not been widely studied. We mined scientific and news/media articles for causal relations among FEW and COVID-19 variables and qualitatively characterized system dynamics. Food systems promoted the emergence and spread of COVID-19, leading to illness and death. Major supply-side breakdowns were avoided (lik
Peer-reviewed industrial hemp research by Ari Gnanasakthy; Amy Barrett; Lindsey Norcross; Denise D’Alessio; Carla DeMuro published in Value in Health (2021).
Endometriosis is characterized by the presence of endometrium-like tissue outside the uterus. The etiology remains largely unknown. Despite adequate treatment, patients can still experience symptoms or side effects resulting in therapy incompliance and in self-management strategies such as dietary measures is increasing. A gluten free diet is thought to be contributory in reducing endometriosis-related pain, thereby optimizing quality of life. However, data is conflicting and currently provides
Peer-reviewed industrial hemp research by Johannes G. Ramaekers; Natasha L. Mason; Stefan W. Toennes; Eef L. Theunissen; Enrico Amico published in Scientific Reports (2022).
There is tremendous interest in the role of the neuroimmune system and inflammatory processes in substance use disorders (SUDs). Imaging biomarkers of the neuroimmune system in vivo provide a vital translational bridge between preclinical and clinical research. Herein, we examine two imaging techniques that measure putative indices of the neuroimmune system and review their application among SUDs. Positron emission tomography (PET) imaging of 18 kDa translocator protein availability is a marker
Peer-reviewed industrial hemp research by Ziv Ben‐Zion; Nachshon Korem; Naomi B. Fine; Sophia Katz; Megha Siddhanta; Melissa Funaro; Or Duek; Tobias R. Spiller; Sarah K. Danböck; Ifat Levy published in Biological Psychiatry Global Open Science (2023).
Public perception surrounding whether cannabis use is harmful during pregnancy often diverges greatly from the recommendations of doctors and healthcare providers. In contrast to the medical guidance of abstinence before, during, and after pregnancy, many women of reproductive age believe cannabis use during pregnancy is associated with little potential harm. Legalization and social cues support public perceptions that cannabis use during pregnancy is safe. Moreover, pregnant women may consider
Such findings support the participation of HDAC enzymes in cognitive and emotional alterations induced by binge alcohol consumption during gestation and lactation and would indicate potential benefits of HDAC inhibitors for some aspects of foetal alcohol spectrum disorders.
Peripheral inflammatory conditions, including those localized to the gastrointestinal tract, are highly comorbid with psychiatric disorders such as anxiety and depression. These behavioral symptoms are poorly managed by conventional treatments for inflammatory diseases and contribute to quality of life impairments. Peripheral inflammation is associated with sustained elevations in circulating glucocorticoid hormones, which can modulate central processes, including those involved in the regulatio
Altogether, these results indicated that EA ameliorated PSD-like behaviors in mice, improved cognitive dysfunctions after PSD, and promoted mitochondrial biogenesis by activating CB1R, a novel mechanism underlying EA's antidepressant-like effects in treating PSD.
In participants post-COVID-19 with persistent neuropsychiatric symptoms, the lower-than-normal tNAA and glutamate + glutamine indicate neuronal injury, while the lower-than-normal myo-inositol reflects glial dysfunction, possibly related to mitochondrial dysfunction and oxidative stress in Post-COVID participants with persistent neuropsychiatric symptoms.
Chronic pruritus that lasts for over 6 weeks can present in various forms, like papules, nodules, and plaque types, with prurigo nodularis (PN) being the most prevalent. The pathogenesis of PN involves the dysregulation of immune cell-neural circuits and is associated with peripheral neuropathies, possibly due to chronic scratching. PN is a persistent and challenging condition, involving complex interactions among the skin, immune system, and nervous system. Lesional skin in PN exhibits the infi
This comprehensive review delineates the extensive roles of <i>Akkermansia muciniphila</i> in various health domains, spanning from metabolic and inflammatory diseases to neurodegenerative disorders. <i>A. muciniphila</i>, known for its ability to reside in the mucous layer of the intestine, plays a pivotal role in maintaining gut integrity and interacting with host metabolic processes. Its influence extends to modulating immune responses and potentially easing symptoms across several non-commun
<b>Objectives:</b> The identification of clinically relevant subtypes of insomnia is important. Including a comprehensive literature review, this study also introduces new phenotypical relevant parameters by describing a specific insomnia cohort. <b>Methods:</b> Patients visiting the sleep center and indicating self-reported signs of insomnia were examined by a sleep specialist who confirmed an insomnia diagnosis. A 14-item insomnia questionnaire on symptoms, progression, sleep history and treat