Hemp Research — Page 193

Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.

Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety (2021)

Mounting evidence support the potential benefits of functional foods or nutraceuticals for human health and diseases. Black cumin (<i>Nigella sativa</i> L.), a highly valued nutraceutical herb with a wide array of health benefits, has attracted growing interest from health-conscious individuals, the scientific community, and pharmaceutical industries. The pleiotropic pharmacological effects of black cumin, and its main bioactive component thymoquinone (TQ), have been manifested by their ability

Adult Cancer Pain, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology (2019)

In recent years, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain have undergone substantial revisions focusing on the appropriate and safe prescription of opioid analgesics, optimization of nonopioid analgesics and adjuvant medications, and integration of nonpharmacologic methods of cancer pain management. This selection highlights some of these changes, covering topics on management of adult cancer pain including pharmacologic interventions, nonpharmaco

Gut Microbiome: Profound Implications for Diet and Disease (2019)

The gut microbiome plays an important role in human health and influences the development of chronic diseases ranging from metabolic disease to gastrointestinal disorders and colorectal cancer. Of increasing prevalence in Western societies, these conditions carry a high burden of care. Dietary patterns and environmental factors have a profound effect on shaping gut microbiota in real time. Diverse populations of intestinal bacteria mediate their beneficial effects through the fermentation of die

Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy (2019)

Although a significant reduction in seizure frequency was achieved for dogs in the CBD group, the proportion of responders was similar between groups. Given the correlation between plasma CBD concentration and seizure frequency, additional research is warranted to determine whether a higher dosage of CBD would be effective in reducing seizure activity by ≥ 50%.

Early childhood epilepsies: epidemiology, classification, aetiology, and socio-economic determinants (2021)

Epilepsies of early childhood are frequently resistant to therapy and often associated with cognitive and behavioural comorbidity. Aetiology focused precision medicine, notably gene-based therapies, may prevent seizures and comorbidities. Epidemiological data utilizing modern diagnostic techniques including whole genome sequencing and neuroimaging can inform diagnostic strategies and therapeutic trials. We present a 3-year, multicentre prospective cohort study, involving all children under 3 yea

Glut1 Deficiency Syndrome (Glut1DS): State of the art in 2020 and recommendations of the international Glut1DS study group (2020)

Glut1 deficiency syndrome (Glut1DS) is a brain energy failure syndrome caused by impaired glucose transport across brain tissue barriers. Glucose diffusion across tissue barriers is facilitated by a family of proteins including glucose transporter type 1 (Glut1). Patients are treated effectively with ketogenic diet therapies (KDT) that provide a supplemental fuel, namely ketone bodies, for brain energy metabolism. The increasing complexity of Glut1DS, since its original description in 1991, now

The Pharmacology and Clinical Efficacy of Antiseizure Medications: From Bromide Salts to Cenobamate and Beyond (2021)

Epilepsy is one of the most common and disabling chronic neurological disorders. Antiseizure medications (ASMs), previously referred to as anticonvulsant or antiepileptic drugs, are the mainstay of symptomatic epilepsy treatment. Epilepsy is a multifaceted complex disease and so is its treatment. Currently, about 30 ASMs are available for epilepsy therapy. Furthermore, several ASMs are approved therapies in nonepileptic conditions, including neuropathic pain, migraine, bipolar disorder, and gene

Incidence and phenotypes of childhood-onset genetic epilepsies: a prospective population-based national cohort (2019)

Epilepsy is common in early childhood. In this age group it is associated with high rates of therapy-resistance, and with cognitive, motor, and behavioural comorbidity. A large number of genes, with wide ranging functions, are implicated in its aetiology, especially in those with therapy-resistant seizures. Identifying the more common single-gene epilepsies will aid in targeting resources, the prioritization of diagnostic testing and development of precision therapy. Previous studies of genetic

Practice guideline recommendations summary: Treatment of tics in people with Tourette syndrome and chronic tic disorders (2019)

Forty-six recommendations were made regarding the assessment and management of tics in individuals with Tourette syndrome and chronic tic disorders. These include counseling recommendations on the natural history of tic disorders, psychoeducation for teachers and peers, assessment for comorbid disorders, and periodic reassessment of the need for ongoing therapy. Treatment options should be individualized, and the choice should be the result of a collaborative decision among patient, caregiver, a

Mechanical Characterization and Predictive Analysis of Flax Fiber/PLA Honeycomb Sandwich Structures in FDM Additive Manufacturing (2024)

The improved recyclability, renewability, and biodegradability of natural fibre composites have made them a hot commodity in recent years. Fused Deposition Modelling (FDM) is extensively employed in additive manufacturing technology that can produce simple and complex structures. Using the FDM procedure, this research created honeycomb sandwich structures out of flax and PLA and studied their mechanical behaviour. At first, samples of 3D-printed composites and flax fiber/PLA filaments were teste

Formation of Glutinous Biocomposite Materials Filled with Chopped Stalks of Cereal Crops (2023)

The article presents an analysis of the influence of temperature-time parameters of heat treatment on the compressive strength of biocomposite materials, the compositions of which was dried to regulate the moisture content. The samples formed by pressing the prepared composition, based on an aqueous solution of glutin and chopped stalks of cereal crops with a fixed moisture content. Excess moisture content in the composition was reduced by processing in a thermal field at a temperature of 50…60

Effect of fiber length on tensile strength, impact toughness, and flexural strength of Banana Stem Fiber (BSF)-polyester composite for train body (2023)

The study aimed to determine the tensile and impact strength characteristics of the banana steam fiber (BSF)-polyester composite modified with NaOH treatment. The composites were made using the hand lay-up method, varying the length of the BSF fibers to 10 mm, 20 mm, and 30 mm. The fiber was modified by giving 2% NaOH for 1 day to improve the mechanical properties of the composite. The tensile strength tests were carried out using ASTM D638 standards. While impact tests were carried out using AS

Surface Modifications of Natural Fibers for use in Preparation of Biocomposites (2021)

This century has observed unusual improvements in green materials through the development of biocomposites due to anxieties about the atmosphere and sustainability issues. These biocomposites can be effectively disposed of at the final existence without harming the environment, which is impossible with man-made fiber-based polymer composites. The natural fiber is not a problem-free option, and they maintain some shortfall features that are the considerable moisture assimilation and very anisotro

Properties of High-Density Polyethylene-Polypropylene Wood Composites (2022)

We investigated the effects of polymer blend variation on the physical, mechanical, and thermal properties of wood-polymer composites (WPC). We used high-density polyethylene (HDPE) and polypropylene (PP) and a combination of 80% PP, 20% HDPE, and 80% HDPE, 20% PP as polymer blends for WPC formulations to simulate recycled plastics. We used black spruce (Picea mariana Mill.) hammer milled fibers (75–250 μm) at 35 wt% as a filler for all the formulations. A two-step process was used for WPC manuf

New investigation of mechanical properties of a horizontal axis wind turbine blade based on a hybrid composites with kenaf fibers (2020)

The present work aims to assess the benefit of introducing simultaneously kenaf and carbon fibers in a composite wind turbine blade made initially of epoxy glass fiber. After an in-depth analysis of the optimal design of the blade using the Blade Element Momentum theory, an algorithm is generated in order to, firstly, establish the foundation of the blade geometry and secondly, to make a conservative static loading estimation representing a 50-years extreme gust. After performing the blade geome

Effect of Environment on Mechanical Behavior of Thermosetting Composites Reinforced with Bio-filler (Orange Peel Particulate) Materials (2022)

The behavior of natural fiber depends upon different environmental conditions due to its hydrophilic nature. Therefore, this article has focused on the significant consequence of moisture absorption on the mechanical properties of bio-waste (orange peel) reinforced epoxy composites with different weight percentages (10%, 20%, and 30%) in different environmental conditions such as saline water treatment, steam treatment, and subzero temperature. After attaining saturation, the experiments were ca

Influence of Density on the Withdrawal Staple Strength from Hemp Shive Panels (2023)

Particleboards are the main material used in the production of furniture and furnishings. The shortage of wood raw material and the everincreasing amount of particleboards produced suggest a search for alternative raw material sources for this panel type. On the other hand, significant quantities of agro-industrial lignocellulosic residues are available worldwide. Such a type of residue is hemp shives. Basic joints in furniture frames are stapled joints, as it should be said that density is the