Hemp Research — Page 84

Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.

Biopolymer soil stabilization as protection from slope erosion and shallow sliding (2022)

<p>Climate change has a significant impact on slope stability through atmospheric perturbations, water infiltration and soil erosion, which is often accompanied by local or shallow sliding of the slopes. Usually, the erosion is not seen as a stability-treating occurrence, but with time it can develop to a reduction of the shear soil strength and raise in the pore water pressure that can disturb the slope stability.</p><p>In order to overcome these proble

Endocannabinoid System: Overview and Therapeutic Relevance (2021)

The endocannabinoid system (ECS) modulates a variety of physiological processes, attracting considerable attention as a potential target for therapeutic intervention. This complex system is activated by the lipid-derived mediators anandamide and 2-arachidonoyl-sn-glycerol (2-AG), which mainly engage the cannabinoid receptor subtypes 1 (CB1) and 2 (CB2). The biological actions of anandamide and 2-AG are terminated by internalization and intracellular enzymatic hydrolysis catalyzed primarily by th

Sustainability and sound insulation—Impact sound insulation of lightweight floor constructions on base slabs in timber and lightweight solid construction (2025)

Timber construction and lightweight solid elements are sustainable options for modern building design. Lightweight floor constructions are essential for both, with slim, weight-reduced cross-sections enabling material savings and adhering to sustainability principles. In Germany, impact sound insulation requirements are defined in DIN 4109-1 (minimum sound insulation) and DIN 4109-5 (enhanced sound insulation). Floating screeds are necessary for compliance, as soft floor coverings (e.g., carpets

Preliminary Material (2021)

Peer-reviewed industrial hemp research by Droste, Heiko; Hurd, Madeleine published in The Business of News (2021).

NANO-DELIVERY SYSTEMS FOR ENHANCING ORAL BIOAVAILABILITY OF DRUGS (2023)

The two main issues impacting oral delivery are drug solubility and permeability. The FDA adopted the Biopharmaceutics Classification System (BCS) in 2000. The BCS categorizes drugs into four classes based on their solubility and permeability. For permeability improvement and bioavailability, many experimental systems are utilized. Numerous nanocarrier technologies have recently been utilized to increase drug permeability by employing nanocarrier systems such as lipid vesicles, polymeric and lip

Effect of Food on Bioavailability of Drug through Gastro-Retentive Drug Delivery System (2021)

Gastro retentive drug delivery systems (GRDDS) have been explored for controlling the release of the drugs by oral administration. However, since these systems are intended to reside in the gastric region for longer period of time, several factors are expected to hamper the absorption rates of the drug in GRDDS. These systems are in contact with the gastric content for longer time and thus, “Food” is expected to interfere wi

Nano formulations for peptide drug delivery: Overcoming bioavailability and stability challenges (2024)

Peptide-based pharmaceuticals serve as essential therapeutic agents for addressing different conditions such as cancer together with diabetes and infectious diseases. Clinical therapeutic use of peptides is restricted by meager bioavailability, quick enzymatic breakdown, and weak stability. Direct injection and chemical modification methods have revealed a restricted capacity for overcoming these delivery barriers. Nanoformulations establish themselves as promising approaches to address limitati

Extraction and Nano-Sized Delivery Systems for Phlorotannins to Improve Its Bioavailability and Bioactivity (2021)

This review aims to provide an informative summary of studies on extraction and nanoencapsulation of phlorotannins to improve their bioavailability and bioactivity. The origin, structure, and different types of phlorotannins were briefly discussed, and the extraction/purification/characterization methods for phlorotannins were reviewed, with a focus on techniques to improve the bioactivities and bioavailability of phlorotannins via nano-sized delivery systems. Phlorotannins are promising natural

Innovative Strategies to Enhance the Bioavailability of Cannabidiol: Nanotechnology and Advanced Delivery Systems (2025)

Cannabidiol (CBD), a phytocannabinoid with therapeutic potential for neurological and other conditions, faces significant challenges in bioavailability due to its low water solubility, high lipophilicity, and extensive first-pass metabolism. Researchers have developed advanced nanodelivery systems addressing these limitations to enhance CBD’s absorption, stability, and efficacy. This review provides not only a comprehensive summary of current nanotechnological delivery strategies for CBD, includ

Comparative Bioavailability Study of Jaspine B: Impact of Nano-Liposomal Drug Delivery System on Pharmacokinetics (2025)

Jaspine B, an anhyrophytosphingosine, has potent anticancer properties. However, it exhibits low oral bioavailability, reducing therapeutic effects despite its cytotoxicity. This study aimed to address this issue by improving the pharmacokinetics of Jaspine B through liposomal formulation. Jaspine B liposomes were prepared using microfluidic techniques and characterized using transmission electron microscopy (TEM). A sensitive and selective LC-MS/MS method was developed and validated to quantify

Formulation and Evaluation of Solid Self-Nanoemulsifying Drug Delivery System of Cannabidiol for Enhanced Solubility and Bioavailability (2025)

Background/Objectives: This study aims to develop a solid self-nanoemulsifying drug delivery system (SNEDDS) to enhance the solubility and oral bioavailability of cannabidiol (CBD). Methods: According to the solubility of CBD and pseudo-ternary phase diagrams of the different ingredients, an oil (medium-chain triglyceride, MCT), mixed surfactants (Labrasol, Tween 80), and a co-surfactant (Transcutol) were selected for the SNEDDS. CBD-loaded SNEDDS formulations were prepared and characterized. Th

Nano-formulations: Recent Trends for Ocular Bioavailability Enhancement (2022)

Eye is a critical part of the body that is readily available and with damage having direct effects on the life of an individual. Delivery of ocular drugs always remain challenging for healthcare professionals and scientists all over the world due to the challenges that dynamic opthalamic environment provides. These challenges involves different barriers like corneal epithelium, corneal stroma, sclera and other bio-membranes (static barriers), choroidal or conjunctival blood flow, lymphatic clear