Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
Background: Anxiety is a psychiatric disorder that causes many problems in life such as poor concentration, sleep disturbance, and feelings of unease to anticipate future threats. The hypothalamus is a part of the limbic system that regulates stress. The orexinergic system, naturally produced in the hypothalamus, is associated with anxiety and depression which is induced by stress. Andrographolide has antioxidants and anti-inflammation properties that are possibly effective in preventing stress-
Post-traumatic Stress Disorder (PTSD) is a psychiatric disease that arises in individuals who have experienced a traumatic event such as combat exposure, childhood physical abuse, sexual violence, physical assault, an accident, etc. Being difficult to diagnose and treat, PTSD is actively studied in areas of medicine, psychiatry, biochemistry, and rehabilitation. PTSD is characterized by significant comorbidity and is accompanied by depression and anxiety. Current treatment strategies for PTSD sy
Traumatic brain injury (TBI), even when mild, has been associated with the presence of depression. Depression is a mood disorder characterized by persistent negative thoughts and sadness and is challenging to treat due to the multiple mechanisms involved in its pathophysiology, including increased nitric oxide (NO) levels. There are no completely safe and effective pharmacological strategies to treat this disorder. <i>Mucuna pruriens</i> (MP) has been shown to possess neuroprotective properties
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
Abstract Background Pain and sleep disturbances are primary reasons for medicinal cannabis use. Cannabis influences both pain and sleep through its modulation of the endocannabinoid system, which regulate pain pathways and sleep regulation. Despite their interconnected roles, the effects of cannabis and chronic pain on sleep architecture are studied mainly in isolation. An integrated understanding is needed to guide use and minimize risks in this population. Objective Our primary aim was to exam
Peer-reviewed industrial hemp research by Anne Katrin Schlag; David Nutt; Michael T. Lynskey published in Expert Review of Pharmacoeconomics & Outcomes Research (2024).
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The exploration of heterocyclic compounds and their fused analogs, featuring key pharmacophore fragments like pyridine, thiophene, pyrimidine, and triazine rings, is pivotal in medicinal chemistry. These compounds possess a wide array of biological activities, making them an intriguing area of study. The quest for new neurotropic drugs among derivatives of these heterocycles with pharmacophore groups remains a significant research challenge. The aim of this research work was to develop a synthes
Peer-reviewed industrial hemp research by Katrin Skala; Thomas Trabi; Martin Fuchs; Ralf Gößler; Christian-Wilhelm Haas-Stockmair; Nicole Kriechbaumer; Monika Leitner; Nora Ortner; Melanie Reiter; Christian P. Müller published in Neuropsychiatrie (2022).
Post-COVID prevalence's is estimated at 10 % in the general population. The neuropsychiatric symptoms, which are frequent (up to 30 %), can severely affect the quality of life of patients affected by this condition, notably by significantly reducing their working ability. To date, no pharmacologic treatment is available for post-COVID, apart from symptomatic treatments. A large number of pharmacological clinical trials for post-COVID are underway since 2021. A number of these trials targets neur
Mental and physical health-related motives reflect potential intervenable factors that predict PCU in emerging adulthood among EA cannabis users with histories of childhood trauma. Results highlight the importance of and value for assessing a wide range of motives and PCU outcomes to target and address areas for intervention.
Stress plays a central role in functioning for all life forms. As humans, we experience stress in a multitude of ways through various types of stimuli. Due to the constancy of stressors in our lives, the nervous system has learned to allosterically adapt to the stimuli, but when the body cannot adapt, chronic stress can have morphological and degenerative impacts on neuroanatomy and cognitive function that may or may not be reversible. This literature review aimed to identify the specific neuroa
Peer-reviewed industrial hemp research by Ayshe Sahinovic; Namson S. Lau; Angelo Sabag; Rebecca Gordon; Amanda J. Cox; Katie Walker; Christopher Irwin; Ben Desbrow; Nathan A. Johnson; Paul J. Austin published in Sports Medicine - Open (2025).
<b>Rationale and Objectives:</b> Ethanol acts directly on the α7 Nicotinic acetylcholine receptor (α7). Adolescent-binge alcohol exposure (ABAE) produces deleterious consequences during adulthood, and data indicate that the α7 receptor regulates these damaging events. Administration of an α7 Negative Allosteric Modulator (NAM) or the cholinesterase inhibitor galantamine can prophylactically prevent adult consequences of ABAE. The goals of the experiments were to determine the effects of co-admin
TMT B may be sensitive to acute cannabis consumption in medicinal cannabis patients. However, further research is needed to determine the nature and duration of these effects, and whether such effects vary depending on the population studied (e.g., regular vs. new users).
A Cannabis sativa, popularmente conhecida como "Cânhamo da Índia", possui um notável potencial terapêutico apesar de suas propriedades psicoativas. Com uma longa história de uso para nutrição, rituais religiosos, práticas médicas e recreação, a cannabis medicinal é permitida em alguns estados dos EUA e países como Portugal, Holanda e Israel para mitigar sintomas de câncer, AIDS, esclerose múltipla, síndrome de Tourette e convulsões epiléticas. No Brasil, sua utilização é obtida por meio de pedid
These findings contextualise DBC-P score changes in relation to outcomes from other interventions and parent carer and professional views. Which MCID value to choose depends on what factors are prioritised for an intervention.
A new focus on the actual therapeutic drugs its pretend with this Mini Review acting on trigeminal neuralgia (TN) evaluating their efficacy as also side effects. Besides the common search sources, reviews on trials meta-analyses belong to drug therapy for Trigeminal Neuralgia (TN); other important review manuscript were added from its publication lists and case reports to take this review.Interesting, that carbamazepine, among of the TN´s drugs is the exception that had been adequately studied.
Future research with larger samples might consider adopting this novel remote study design to assess the acute effects of high-potency cannabis use on different measures of emotion regulation and other health outcomes.
Peer-reviewed industrial hemp research by Ron D. Hays; Patricia M. Herman; Nabeel Qureshi; Anthony Rodriguez; Maria Orlando Edelen published in Pain Management Nursing (2023).
Cannabis sativa contains phytocannabinoids that are psychoactive and neurotoxic (delta-9-tetrahydrocannabinol: Δ9THC) or nonpsychoactive and presumptively neuroprotective (cannabidiol: CBD). Along with rising legalization, availability, and demand, the Δ9THC:CBD ratio also has increased. Cannabis legalization means that use will likely increase in pregnant or breastfeeding women, affecting all stages of brain and neurodevelopment of their offspring. Δ9THC exposure in utero or during development
Background: The word "epilepsy" refers to a category of chronic CNS illnesses characterised by spontaneous occurrence of seizures, which are typically accompanied by loss of consciousness and uncontrollable shaking of the body (convulsions). Epilepsy is one of the most commonly occurring non-communicable neurological disorder that affects people of all age groups. By preventing discharge and inducing hypnosis, anticonvulsant medications are used to manage convulsions. The medication used for the
Abstract Background & Aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta-9-tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5mg THC). Design Data from the CannTeen study, a longitudinal observational study consisting of five assessments over a 12-month period. Setting London, UK. Participants Participants were n = 65 adults
Peer-reviewed industrial hemp research by J. Megan Ross; Bruna Cuccurazzu; Dylan Delmar; Célia Martins Cortez; Gabriel Castillo; Dean T. Acheson; Dewleen G. Baker; Victoria B. Risbrough; Daniel M. Stout published in npj Mental Health Research (2025).