Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
Doxorubicin (DOX) is an effective drug for the treatment of solid tumors and hematological malignancies in both children and adults. The most serious side effect is doxorubicin-induced cardiotoxicity (DIC), which can lead to cardiomyopathy and irreversible and highly fatal cardiac decompensation. The precise mechanisms underlying DIC are not fully understood, and currently, no fully effective preventive or therapeutic strategies exist. Drug repositioning has emerged as a promising approach to mi
As the baby boomer cohort ages, they have an ever-increasing number of comorbidities and associated poly-pharmaceutical treatment needs. The challenge for healthcare providers is to stay current of advancements in providing for this aging population. Baby boomers can expect a longer life expectancy than any previous generation. Yet, longevity has not correlated with better health. This cohort is noted for being goal driven and more self-assured than younger generations. They are resourceful and
Internationally, teenage pregnancy has been recognized as a major pertinent issue. Lack of adequate family support affects the emotional well-being of the pregnant student mother as well as the unborn and/or the newborn baby. Furthermore, student motherhood hinders the chance of the student mother from completing her studies. In Kenya, teenage pregnancy thwarts achievements in the education of the girl child. The objective of this study was to establish the effect of spiritual intervention on st
Peer-reviewed industrial hemp research by Chad Sloley; Caroline Bell; Edward A. Shipton; Jonathan Williman; Joseph N Jarvis published in Pain and Therapy (2025).
Objetivo: Identificar os estudos científicos sobre o uso de derivados canabinoides no tratamento de distúrbios neurológicos por pacientes idosos. Métodos: Revisão integrativa da literatura nas plataformas de dados PubMED, Portal Regional Biblioteca Virtual em Saúde, e Periódicos CAPES, realizada entre agosto e dezembro de 2023. Foram utilizados descritores do Medical Subject Headings: "aged", "therapeutic", "cannabis”, "parkinson's Disease”, "epilepsy", "dementia", "bipolar disorders" e "depress
Общение считается одной из базовых потребностей человека. Долгое время одиночество и социальная изоляция считались преимущественно психосоциальной проблемой. Однако в последние годы появляется все больше свидетельств о возможном влиянии одиночества и социальной изоляции на развитие и клиническое течение соматических заболеваний. Цель работы — изучение современных данных литературы о медицинских последствиях одиночества и социальной изоляции у лиц пожилого возраста. Анализ данных показал, что оди
Background: Women with PMS have higher rates of substance use disorders but underlying mechanisms remain poorly understood. Research on the links of PMS to problematic substance use has largely omitted consideration of cannabis use. Design/Method: To fill these gaps, 87 cannabis using women (mean age = 28.9 years) completed a cross-sectional survey involving self-reports on their PMS symptoms on the Pre-Menstrual Scale – Short Form (PMS-SF), their usual motives for cannabis use on the Marijuana
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
AMPA.Esses eventos culminam com a ativação dos canais de cálcio dependentes de voltagem do tipo L (VDCC), aumento do influxo de cálcio e liberação de BDNF na fenda sináptica (DUMAN
O canabidiol (CBD), composto da planta Cannabis sativa, tem sido investigado em estudos com animais e humanos. Esses estudos corroboram a hipótese do efeito ansiolítico deste composto, bem como de sua interferência na reconsolidação e extinção de memórias aversivas. O objetivo desse estudo foi avaliar se a administração de 300 mg de CBD, antes da rememoração do evento traumático, atenuaria os sintomas ansiosos produzidos por essa rememoração em pessoas diagnosticadas com transtorno de estresse p
Background: Children on the autism spectrum may be at higher likelihood of poorer oral health or experience difficulties with dental health care. However, which children may be more vulnerable is still unknown. Aim: To investigate parental reports of oral health and dental service needs of children diagnosed with autism and explore relationships with clinical phenotypes. Design: Participants (n=140) were parents of children on the spectrum who had participated in a large biobank, the Australian
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
Case Presentation: AGRB, male, 9 years old, 52kg, previously healthy, born and raised in Pirambu, Bebedouro village, Sergipe.Adtted on 10/09/2022 to the pediatrics sector of the Sergipe Emergency hospital, reporting headache, fever and vomiting for 7 days, with subsequent evolution with pain in the posterior region of the right thigh, in addition to low back pain.Physical examination showed normal breathing and heart rate.Decreased strength in lower limbs, being worse on the left side.No patella
Case Presentation: AGRB, male, 9 years old, 52kg, previously healthy, born and raised in Pirambu, Bebedouro village, Sergipe.Adtted on 10/09/2022 to the pediatrics sector of the Sergipe Emergency hospital, reporting headache, fever and vomiting for 7 days, with subsequent evolution with pain in the posterior region of the right thigh, in addition to low back pain.Physical examination showed normal breathing and heart rate.Decreased strength in lower limbs, being worse on the left side.No patella
Case Presentation: AGRB, male, 9 years old, 52kg, previously healthy, born and raised in Pirambu, Bebedouro village, Sergipe.Adtted on 10/09/2022 to the pediatrics sector of the Sergipe Emergency hospital, reporting headache, fever and vomiting for 7 days, with subsequent evolution with pain in the posterior region of the right thigh, in addition to low back pain.Physical examination showed normal breathing and heart rate.Decreased strength in lower limbs, being worse on the left side.No patella
<p>Introduction: Adolescent-onset cannabis use is rising in the era of marijuana legalization. Recent imaging studies have identified neuroanatomical differences between adult cannabis users and controls that are more prominent in early-onset users. Other studies point to sex-dependent effects of cannabis.</p><p>Methods: A systematic review following PRISMA guidelines and subsequent effect-size seed-based d mapping (SDM) meta-analyses were conducted to investigate relationships
Substance use disorders (SUDs) can be defined as patterns of symptoms caused by the abusive consumption of recreational or prescribed substances that an individual continues to use despite their negative effects. Oxidative stress is one of the main pathophysiological processes occasioned by SUDs in different brain areas. Oxidative damage and subsequent deleterious symptoms can happen because of the consumption of psychoactive drugs, both stimulants and depressants. This chapter focuses on SUDs a
The brain remains the most complex organ within the mammalian body with an immense capacity for plasticity and change throughout an individual’s life history. This review examines brain-derived neurotrophic factor (BDNF) and endocannabinoid (eCB) signalling cross-talk within a variety of neurodevelopmental, genic, and plastic processes that occur in the brain. The action of eCB and BDNF cross-talk in embryonic and adult neurogenesis is a bidirectional dynamic process of high complexity that faci
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
The use of drugs for recreational purposes has changed dramatically, involving a variety of substances such as opioids, hallucinogens, and cannabinoids. Although these substances are often initially used for recreational purposes, their psychoactive properties can contribute to the development of addiction, withdrawal syndromes, and significant physical and mental health complications. The mechanisms behind addiction, symptoms of withdrawal, and the pathophysiology of frequently abused recreatio
These novel findings suggest that baseline inflammatory status influences the relationship between cannabis use, negative affect, and sleep quality in people with anxiety.
Introduction: Patients with cirrhosis often present with pain as a common complaint. Pharmacological pain management safety depends on the excretion and metabolism of drugs by the kidney and the liver. The analgesic choice in cirrhotic patients can be tremendously challenging, especially in patients with hepatorenal syndrome, a potentially reversible renal impairment associated with an increased drug accumulation and a high risk of potential toxicity. Choice and dose of medications depend on var
Abstract Although vast scientific progress has been made, the current pharmacotherapy of depression is still not fully effective. In adults, depressive disorders are among the most common diseases in industrialized countries, impact upon all aspects of family and working life and significantly disturb social functioning. Moreover, increasingly, they affect children and teenagers. Depressive disorders have a complex etiology. This includes a number of mechanisms that are not yet fully understood.
Cannabidiol (CBD) has been suggested to have a therapeutic role for certain mental health conditions despite a lack of empirical evidence (Khan et al. 2020; Bonaccorso et al. 2019; Kirkland et al. 2022). The aim of the RCT (DRKS00030971) was to assess the effect of a daily sublingual application of a low dose over-the-counter 10% full spectrum CBD-oil over 30 days, compared to a placebo-oil and a no-treatment control group without application of any oil on perceived stress and psychological dist