Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
Autism spectrum disorder (ASD) is characterized by challenges in social communication, difficulties in understanding social cues, a tendency to perform repetitive behaviors, and restricted interests. BTBR T<sup>+</sup> Itpr3<sup>tf</sup>/J (BTBR) mice exhibit ASD-like behavior and are often used to study the biological basis of ASD. Social behavior in BTBR mice is typically scored manually by experimenters, which limits the precision and accuracy of behavioral quantification. Recent advancements
Many people in the USA have lost their lives or become addicted to opioids via prescription opioids given for chronic pain. The chronic pain epidemic has emerged due to a convergence of factors, including the medicalization of pain as well as injuries happening in the workplace, in the home, or during recreation. Opioid prescriptions rose precipitously from the late 1990’s through to approximately 2020, and despite public awareness, still are increasing. This review examines literature on integr
Around the world, 50 million people suffer with epilepsy; it significantly burdens society in terms of finances, society, and health. Our comprehension of the pathophysiological processes causing the illness and the factors affecting its prognosis has significantly advanced during the last ten years. Around a third of patients are still resistive to medical intervention, despite the fact that the number of antiepileptic drugs has expanded dramatically over the past 20 years. The ability of nanot
Early in the pandemic, clinicians recognized an overlap between Long COVID symptoms and dysautonomia, suggesting autonomic nervous system (ANS) dysfunction. Our clinical experience at Johns Hopkins with primary dysautonomia suggested heritability of sympathetic dysfunction, manifesting primarily as hyperhidrosis and as other dysautonomia symptoms. Whole exome sequencing revealed mutations in genes regulating electrical signaling in the nervous system, thus providing a genetic basis for the sympa
Alcohol consumption during pregnancy and lactation remains a significant global issue. Preventive policies have proven insufficient, and consumption rates remain high, mainly due to a lack of awareness, the misconception that only high alcohol intake harms the fetus, inconsistent medical advice, and pre-existing alcohol use disorders. Alcohol consumption is linked to child harm during critical stages of development. Using a recently published model of fetal alcohol spectrum disorder (FASD) devel
Background: Depression is a prevalent psychiatric disorder characterized by heterogeneous symptoms that can last a lifetime and remain even after several courses of antidepressant treatments. Vulnerability to depression is associated with long-lasting changes in the transcriptional profile of the nucleus accumbens (NAcc), a brain region involved in reward and mood regulation. Methods: Here, we characterized the enduring changes in histone modifications in the NAcc of mice exposed to chronic soci
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
Peer-reviewed industrial hemp research by Giuseppe De Simone; Michele De Prisco; Vincenzo Oliva; Licia Vellucci; Mariateresa Ciccarelli; Benedetta Mazza; Giovanna Fico; Michele Fornaro; Felice Iasevoli; Eduard Vieta published in Molecular Psychiatry (2025).
Peer-reviewed industrial hemp research by Zachary B. Millman; Daphne J. Holt; Matcheri S. Keshavan; Larry Seidman; Alan Breier; Martha E. Shenton; Döst Öngür; Samantha V. Abram; Jessica P.Y. Hua; Spero Nicholas published in Neuropsychopharmacology (2023).
O presente estudo aborda o benefício do uso terapêutico do Canabidiol (CBD) no tratamento da Esclerose Múltipla (EM), uma doença neurológica autoimune, inflamatória e crônica. Pacientes com EM há muito tempo recorrem a terapias complementares para controlar os sintomas, uma vez que os medicamentos licenciados controlam apenas parcialmente a doença. Os tratamentos farmacológicos existentes diminuem o avanço dessa patologia, reduzindo a atividade inflamatória e a ocorrência dos surtos que são gera
It is important to address the effects of trauma in the K-12 education system because those effects can have crippling effects on how students succeed academically and in life. The research uncovered in this review of literature pointed to the fact that there are inconsistencies in even defining trauma. There are multiple versions of how to categorize trauma and various ways they manifest, with only some of them being observable. The methods used for addressing trauma have their positives and ne
The issue of illegal drug production and trafficking represents one of the major challenges of modern society and the sustainable development of mankind. Achieving sustainable development goals such as good health and well-being (SDG 3), sustainable cities and communities (SDG 11) and peace, justice, and strong institutions (SDG 16) would be much more difficult if the issue of drugs-related crime were neglected. This chapter highlights problems associated with this type of criminality from both
Background: Weed smoking is a vastly unfavorable and perilous practice that can lead to various diseases, but it can also have beneficial effects on the human body. It comprises mainly two bioactive cannabinoids, delta 9-tetrahydrocannabinol and cannabidiol; they have both adverse and beneficial effects on human health. Objective: This study aims to identify the proteins interacting with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) to predict their potential influences on the human b
Background: Canada legalized the use of cannabis for recreational purposes in October 2018. To ensure public health and safety, the Cannabis Act was also introduced by the Government of Canada in 2018. This Act does not permit smoking cannabis in restricted areas. However, people still smoke in public places, thus, exposing the general public to second-hand cannabis smoke (SHCS). As cannabis is an emerging topic and the legalization of cannabis for recreational use is still recent, the long-term
Symptoms of fibromyalgia (FM) fluctuate and vary in severity. The current study aimed to evaluate the efficacy of palmitoylethanolamide (PEA) and acetyl-L-carnitine (ALC) in FM patients over a 24-month period and to investigate the mediating function of pain catastrophizing subdomains in unfavorable relationships with disease severity levels in patients with FM. Patients were evaluated at baseline, after 12 months, and after 24 months, using different patient-reported measures (FIQR, FASmod, PSD
Breast milk provides significant health benefits to both infants and mothers, offering protection against infections and enhancing cognitive development. This paper examines the complex effects of substance use disorder (SUD) during pregnancy and lactation, focusing on the pharmacokinetics of drug transfer into breast milk. It highlights the mechanisms by which drugs enter milk, emphasizing the roles of passive diffusion and active transport, particularly through breast cancer resistance protein
Cannabis is a commonly used illicit substance, often consumed for its potential to promote relaxation and alleviate anxiety. This study employed the light-dark transition test to examine the effects of acute delta-9-tetrahydrocannabinol (THC) exposure on anxiety-like behavior in larval zebrafish. At 7 days post-fertilization, zebrafish larvae were exposed to one of several treatments: egg water (control), 1% dimethyl sulfoxide (DMSO, vehicle control), 100 mg/L caffeine in egg water, 10 mg/L alpr
Objective: Expose existing therapies for the treatment and monitoring of endometriosis, delving into the use of cannabidiol as a new therapeutic form.Methods: A narrative review of the literature was carried out based on 37 articles that ranged between 2004 and 2022 between March and May 2023.The bibliography included the Portuguese and English languages, preferably from the last 5 years, and were taken from the SciElo databases, PubMed, Web of Science and Scopus.Results: The clinical picture of
How to determine suitable animal models of anxiety disorders and post-traumatic stress disorders (PTSD) for screening anxiolytic drugs and linking preclinical and clinical research is a crucial issue. This review paper provides background knowledge and critical determination to the animal models for discussing this issue. Moreover, this article analyzes the characteristics, properties, advantages, and disadvantages of various animal models of anxiety disorders and PTSD. It offers an overview of
Peer-reviewed industrial hemp research by Sanaz Vaziri; Meghan E. McGarry; A. Cuneo; M. Chan; E. Gibb; K. Iwanaga; F. Neemuchwala; N. Ly published in Journal of Cystic Fibrosis (2022).
Introduction. The popular use of marijuana and its components (THC and CBD) for medicinal purposes is often regarded as irresponsible and ignorant. However, in this paper, it is conceptualized and studied as medical knowledge of self-care, in which it is linked to different therapeutic knowledge from conventional and alternative medicine to treat anxiety. Objective. This article reports on a qualitative research project designed to analyze the practices and risks of self-medication with CBD, and
Benzodiazepines (BZDs) are some of the most commonly prescribed medications in the United States and are currently classified as schedule IV-controlled substances. Originally patented in 1958, Librium became the first BZD synthesized and set the stage for what would become a major change in medical practice. Since their introduction, BZDs were meant to replace barbiturates, a precursor family with highly addictive properties and lethal overdose consequences. Within the past twenty years, it has
Medical marijuana (Cannabis sativa) has been used since ancient time. Its use is written in medical books from china, India and even the Mesopotamian era. In these records, the use of marijuana (Cannabis sativa) is not only as a medicine, but also as a food ingredient and a ritual tool. A popular issue in Indonesia today is about legalization of medical marijuana. Marijuana is a class I narcotic which is written in the law. Cannabis has a very high potential to cause addicted and not used for th
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder. Significant progress has been made in the intervention and treatment of ASD. This review systematically summarizes five major categories of mainstream ASD treatment approaches. This article outlines the theoretical basis and therapeutic effects of each intervention method, discusses their advantages and limitations, and analyzes and forecasts future development directions. Due to the lack of specific treatment