Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
Severe behavioral problems (SBPs) are common contributors to morbidity and reduced quality of life for adults with intellectual and developmental disabilities (IDD) and their families. Current medications for SBPs show equivocal effectiveness and are associated with a high risk of side effects. New and safe treatments are urgently needed. While preliminary studies suggest that medical cannabinoids, particularly the synthetic cannabinoid nabilone, are plausible treatment options for SBPs in adult
Herbal remedies are increasingly recognized for their therapeutic potential in treating lifestyle diseases and complementing traditional medical approaches.This review synthesizes recent research findings highlighting the safety, effectiveness, and mechanistic insights of herbal remedies in contemporary clinical practice.Studies affirm their efficacy in managing prevalent conditions such as diabetes, obesity, heart disease, hypertension, and stress, attributing these benefits to diverse mechanis
Cannabis use (CU) motives among older adults (OA) could be an important indicator of broader mental health. OA ages 60+ (N = 78) reported on CU, alcohol consumption, and mood and anxiety. Coping, enhancement, social, conformity, expansion, and routine motives were assessed. Relationships among CU, alcohol consumption, and screenings for Cannabis Use Disorder (CUD), Alcohol Use Disorder (AUD), depression, and anxiety were examined. OA who screened positive for CUD were not different in CU frequen
Peer-reviewed industrial hemp research by R Sullender; R. Gina Silverstein; Donnie Goodwin; Asha B. McClurg; Erin T. Carey published in Case Reports in Women s Health (2024).
Dysbiosis of the gut microbiota may lead to a wide range of metabolic, neurological, intestinal and cardiovascular disorders and even to tumorigenesis. Evidence suggests that the gut-brain axis (GBA) plays a crucial role in the treatment of these diseases. Many plant-derived natural actives modulate the gut microbiota and its metabolites, gut hormones and neurotransmitters through a variety of mechanisms, and these actions contribute to the alleviation of irritable bowel syndrome, type 2 diabete
These informed assertions suggest that members of the oncologic community should grapple with the extent to which they feel comfortable with both the nature and degree of counsel adults with cancer receive through dispensaries.
To date, no psychotropic medication has shown to effectively halt progression to psychosis among individuals at Clinical High-Risk for psychosis (CHR), fueling the search for novel therapeutic agents. Recent evidence supports Palmitoylethanolamide (PEA) signaling as a potential psychosis biomarker, also indicating a therapeutic role for its supplementation in the treatment of psychotic disorders. Nonetheless, the effect of sustained PEA intake in CHR subjects has never been explored so far. We w
The review analyzes the change of the existing paradigm of high radioresistance of the nervous system according tothe results of the study of neuropsychiatric disorders in in the aftermath of the Chornobyl accident in both earlyand remote post-accident period. The participation of the endocannabinoid system in ensuring homeostasis andpathology formation, potential possibilities of using cannabis drugs, agonists and antagonists of endocannabinoidreceptors for the treatment of early and long-term
Cannabis is a known illicit substance that is often used by pregnant women, however its potential impact on the developing embryo is unknown. Thus, this experiment used a zebrafish model to investigate how chronic exposure to cannabis tea affected zebrafish development and behaviour. Zebrafish embryos were exposed to cannabis tea prepared at concentrations of 5, 10 and 15 mg/L for 96 hours. The resulting mortality, hatching duration, morphological abnormalities, startle response, light-dark pref
<title>Abstract</title> Physical exercise is a non-pharmacological therapy that has been widely used in drug rehabilitation centers for the treatment of methamphetamine (METH). METH caused cognitive impairment and suppresses adult hippocampal neurogenesis (AHN) in experimental animals. Exercise can improve cognitive impairment caused by multiple factors through AHN. However, little is known about the role of AHN and exercise in METH-neurotoxic injury. We aim to investigate whether running could
ObjetivosEl lenguaje corporal, como mecanismo de comunicación, de un paciente con patología Dual en consulta, puede suponer más del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiración,…).La evaluación y actuación del profesional sanitario en lo expuesto anteriormente, así como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, además con implicaciones médico-legales es fundamental, a nivel perici
The issue of combat-related psychological trauma and the development of post-traumatic disorders during wartime are of great significance now. The ongoing conflict with the invasion of neighbouring forces and the large-scale war against Ukraine poses a threat that could extend for years, if not decades, and potentially affect other regions. The constant shelling of border areas, missile attacks, and the dire social, humanitarian, and epidemiological conditions in occupied territories of Kherson,
This paper explores the early marketing practices (1910-1940) of the Swedish cough drop brand Läkerol, demonstrating how it capitalised on the 'spaces of confusion' posed by the product's liminality between food and medicine to create a slick marketing campaign inspired by the tried-and-tested formulas of the food industry. Advertisements used a range of strategies, such as expert and role model testimonials, humorous and serious newsjacking and the introduction of a friend-physician brand masco
Cannabis-induced psychosis (CIP) represents a significant public health concern in the context of increasing global cannabis use and potency. This review synthesizes current evidence on the epidemiology, neurobiological mechanisms, clinical features, and treatment approaches for cannabis-induced psychotic disorders. Recent epidemiological data indicate rising incidence rates of CIP, with estimates ranging from 2.7 to 6.1 per 100,000 person-years in recent studies. The neurobiological mechanisms
Background and Objective: Depression is one of the most frequent mental illnesses all over the world. Gastrodiae rhizoma (GR) has been used as both herbal medicine and functional food in China. Herein, we aim to decipher the pharmacological targets and active components of GR against depression by using network pharmacology, bioinformatic analysis and molecular docking.
There was no evidence suggesting that past-month cannabis users have better or worse physical activity levels compared to non-users in the Belgian population aged 15-64 years.
Peer-reviewed industrial hemp research by Alexander L. Wallace; Marilyn A. Huestis; Ryan M. Sullivan; Natasha E. Wade published in Behavioural Brain Research (2024).
Neurodegenerative disease is characterized by progressive deterioration of function or structure of nerve cells in central nervous system, mainly manifested as declined cognitive function and impaired motor behavior. Its morbidity and mortality continue to increase with age, and cause a heavy economic and social burden. Gut microbiota is proved to influence behavior through the microbiota-gut-brain axis, and possess tight relationship with neurodegenerative disease such as Alzheimer's Disease (A
Obesity is characterized by an excessive imbalance in energy metabolism and is associated with metabolic syndrome. Mammals have two types of adipose tissue: white adipose tissue (WAT) and brown adipose tissue (BAT). These are key factors in regulating the energy balance. Strategies aimed at reducing obesity should encompass not only the prevention of lipid accumulation but also the stimulation of browning in both WAT and BAT, with the aim of enhancing energy expenditure. In this study, the mecha
The adverse events related to the abuse of psychoactive substances identified in children and adolescents and the emerging signals show the need for increased surveillance and the implementation of prevention campaigns adapted to each group of consumers.
Extensive changes in cannabis regulation accompany changing public attitudes toward cannabis use and legalization. Cannabis use is more prevalent when the drug is legal; therefore, there is a substantial need for an evidence-based understanding of the risks associated with cannabinoids. The current chapter reviews the definition of CUD, its prevalence and associated conditions, and the contemporary understanding of its causes to inform policy, prevention efforts, and treatment of CUD in a dynami
There are high rates of substance co-use among AYAs who use tobacco, consistent across cancer history. Unlike previous research, alcohol co-use was associated with lower rates of nicotine dependence, but only for those with major depression. This finding could be related to neurochemical dysregulation due to co-use and warrants further exploration. Future research should also examine more nuanced definitions of substance use including modes, patterns and initiation of use, and explore motivation
\n Social Anxiety Disorder (SAD) is a mental disorder characterized by fear and anxiety in social situations that lead to functioning impairment and suffering. Although a very frequent disorder among the population, some aspects of development and maintenance of SAD are still unclear. This doctoral dissertation is divided into five articles, that aimed to explore some of these gaps in previous studies. The first one describes the Cross-cultural Adaptation and Psychometric Properties of the Brazi
Extinction is a recognized process for extinguishing threat memories; however, the process of extinction can be emotionally challenging, and the effect is usually short-lived. Animal studies have shown that peer presentation can inhibit freezing behavior and prevent return of the threat memories, suggesting that social support may enhance threat extinction. However, the role of social support in maintaining human threat extinction remains unclear. The present study examined the effect of social