Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
This study offers new insights into the potential impact of CU on the development and progression of various PDs, laying the groundwork for targeted interventions to mitigate its effects on mental health.
Managing chronic, refractory nausea and vomiting in advanced cancer patients is challenging, especially when unrelated to cancer treatment. Mirtazapine, a tetracyclic antidepressant, effectively alleviates these symptoms, improving quality of life. It offers a promising palliative care alternative, addressing multiple symptoms and reducing polypharmacy, thereby enhancing patient satisfaction.
In Canada, cannabis was legalized for medical purposes in 2001 and for nonmedical use in 2018, with edibles, concentrates, and topicals following in 2019 under the Canadian Cannabis Act (Bill C-45).[1][1] This legislation regulates the production, distribution, sale, and possession of cannabis,
Fibromyalgia (FM) is a chronic pain disorder characterized by widespread musculoskeletal pain, frequently accompanied by fatigue, sleep disturbances, cognitive dysfunction, and mood disorders. Although the etiology is multifactorial, involving genetic, hormonal, immunological, and environmental contributors, the exact pathophysiological mechanisms remain unclear, and the heterogeneity of symptoms poses significant challenges for diagnosis and management. Diagnostic criteria have evolved over the
Early treatment of these complex disorders can greatly improve patients’ quality of life.
Social class, race, gender, and generation were predictors of well-being associated with marijuana use and its prohibition, indicating an interaction between different dimensions involving the use of illicit substances. Identifying the effects of the use and prohibition of marijuana in promoting well-being, from the conception of drug use as a non-sanctioned occupation, can broaden the understanding of this complex human phenomenon, with health and criminal repercussions, subsidizing the develop

 There is relentless discussion in Germany about the right manner to deal with cannabis and its users. In 1994 and 2004, the Federal Constitutional Court reaffirmed the legal appropriateness of prohibition. However, since then, studies and data about the dangers and effects of cannabis use have quieted alarm, and Europe, alongside the once-prohibitive United States, has had its initial experiences with liberalised use of cannabis. Since the founding of the Schildower Kreis, a network of ex
Alterations or losses to one’s sense of self and identity are identified in the literature as being an important aspect of the lived experience of schizophrenia. Research further implicates regaining a sense of self and identity as playing an important role in recovery and wellbeing in schizophrenia. Despite this, a comprehensive understanding of the specific component processes involved in changes to sense of self and identity in schizophrenia has not been clearly elucidated. The current study
The most common treatment approach for children diagnosed with attention deficit hyperactivity disorder (ADHD) involves drug therapy; however, persuading parents and motivating children in the early stages of treatment is challenging. Consequently, there is a growing interest among parents of children with ADHD in non-drug therapies. Moreover, recent advancements in information and communication technology have increased the accessibility of digital treatments for ADHD and non-drug therapy conte
Los problemas de salud mental hacen parte de las enfermedades no trasmisibles y se les atribuye, con otras enfermedades asociados al bienestar, hasta un 21 % de las muertes mundiales. Por ello, es necesario analizar y establecer la relación riesgo/beneficio de políticas relacionadas con la salud mental, caso de la legalización del consumo de cannabis recreativo en adultos. El cannabis es la droga “ilícita” de mayor consumo en los países occidentales, en esencia por incrementar la sociabilidad y
Depression and obesity are comorbid conditions linked through shared neuroinflammatory and immune mechanisms. This study examined the effects of chronic cannabidiol (CBD) treatment on behavior and neuroinflammatory gene expression in female rats exposed to a combined model of high-fat diet (HFD) and unpredictable chronic mild stress (UCMS). Rats were subjected to an acute HFD for 2 weeks, followed by 4 weeks of UCMS. CBD (10 mg/kg, i.p.) or vehicle was administered during the final 2 weeks of UC
<i>Background: </i>Marijuana is a very common illicit drug used across the United States and around the world. It has many adverse effects on adolescents and societal health. Among adolescents, it can cause chronic brain damage and psychoactive effects. This literature review aims to discuss topics concerning the epidemiology of marijuana use, adverse health consequences, and risk and protective factors. In addition, the concept of resilience was explored in-depth. <i>Review: </i>Most marijuana
El lenguaje corporal, como mecanismo de comunicacin, de un paciente con patologa Dual en consulta, puede suponer ms del 50% del impacto percibido, de todos los mensajes transmitidos cara a cara (gestos, posturas, movimientos, respiracin,). La evaluacin y actuacin del profesional sanitario en lo expuesto anteriormente, as como en manifestaciones de la piel, tatuajes, lesiones y heridas de origen multifactorial, adems con implicaciones mdico-legales es fundamental, a nivel pericial, para que el si
Misidentification delusions are false, fixed beliefs that assign an incorrect identity to a previously familiar or unfamiliar person or place. Such delusions are common in several neuropsychiatric disorders and place a particular burden on individuals with Major Neurocognitive Disorder and their caregivers. No standard pharmacologic or non-pharmacologic treatment approaches have been shown to be consistently effective in addressing this problem. We describe two caregiver-care recipient dyads in
Peer-reviewed industrial hemp research by Britton R. Barbee; Shannon L. Gourley published in Addiction Neuroscience (2022).
Originally postulated in 2001, the impaired Response Inhibition and Salience Attribution (iRISA) model of addiction highlights the prefrontal cortex (PFC, especially the orbitofrontal, dorsolateral, anterior cingulate, and inferior frontal regions) as central to drug addiction symptomatology. Accordingly, drug cues assume a heightened salience and value that overpower alternative reinforcers, with a concomitant decrease in inhibitory control, especially in a drug related context. These processes
presente revisão visa sumarizar os estudos que abordam o uso de fitocanabinóides em pacientes com doenças neuropsiquiátricas, abordando os benefícios e possíveis efeitos adversos que podem ser observados. Foi realizada uma revisão integrativa de literatura com descritores MeSH: Cannabis, Medical Marijuana, Neurology, Neuropsychiatry e as bases de dados: PubMed, MEDLINE, CINAHL, SCOPUS, Web of Science e SciELO. Selecionou-se artigos entre 2015 a 2021 utilizando como critérios de inclusão, artigos
Abstract Rationale Experiencing intrusive distressing memories of a traumatic event(s) is a prominent symptom profile for post-traumatic stress disorder (PTSD). Understanding the neurobiological mechanisms associated with this symptom profile can be invaluable for effective treatment for PTSD. Objectives Here, we investigated the functional role of the nucleus reuniens (RE), a midline thalamic in modulating stressor-related memory. Methods Female Long Evans rats were implanted with a cannula aim
Abstract Adolescent depression is a significant public health concern, yet treatment options remain limited, particularly due to age- and sex-related differences in antidepressant efficacy. This study explored the rapid and long-lasting antidepressant-like potential of psilocybin in adolescent Sprague-Dawley rats, examining acute and repeated oral dosing effects while incorporating sex as a biological variable. An acute administration of psilocybin produced rapid antidepressant-like effects 30 m
There is still much debate about the etiology and remedies of anxiety disorders. Summarizing the current research results will facilitate a deeper understanding of anxiety disorders and uncover suitable treatments. Environmental changes, childhood trauma or physical abuse, and a Mediterranean diet or the microbiome were strongly associated with disease development. Also, the PDE4B gene, other essential loci, and 274 genes' interaction with the environment could potentially cause anxiety. Molecul
Introduction Predictors consistently associated with psychosis liability and course of illness in schizophrenia (SCZ) spectrum disorders (SSD), including the need for clozapine treatment, are lacking. Longitudinally ascertained medication use may empower studies examining associations between polygenic risk scores (PRSs) and pharmacotherapy choices. Objectives To examine associations between PRS-SCZ loading and groups with different liabilities to SSD: individuals with SSD on clozapine, individu
IntroductionSleep quality is increasingly acknowledged as critical for immune function and overall health. Poor sleep can disrupt immune response, elevating inflammation and susceptibility to infection and chronic diseases. Given the prevalence of sleep disturbances across populations, understanding their impact on immune health and overall wellness is essential. Purpose of WorkThis review aims to examine the relationship between sleep quality and immune function by synthesizing findings on how
Peer-reviewed industrial hemp research by Felicia C. Goldstein; Katherine E. Galluzzi; B Bach; Matthew Brown; James F. Smith; J Lubeck; Michelle R. Lent published in Journal of Pain (2024).
Introdução: Estima-se que mais de 300 milhões de pessoas sofram com a depressão, um transtorno mental comum caracterizado por humor deprimido ou perda de prazer ou interesse em atividades por longos períodos de tempo, sendo esta a principal causa de incapacidade em todo o mundo. Objetivo: Verificar a eficácia e os efeitos da Cannabis medicinal no tratamento da depressão, sistematizando e analisando o que vem sendo publicado sobre o tema nos últimos 5 anos e, dessa forma, contribuir para a promoç
<title>Abstract</title> Previous quantitative research has shown that cannabis use, mostly illicit, is used for symptom management amongst those with endometriosis living in Australia or New Zealand, but the drivers and barriers for use of legal, medicinal cannabis in this population are currently unclear. This study sought to investigate, <italic>via</italic> online focus-groups, the perceptions, barriers, drivers, and experiences associated with cannabis use, whether legal or illicit, amongst