Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.
The Altered States Database (ASDB) is an open science project, containing psychometric questionnaire data on altered states of consciousness experiences induced by diverse means. The database was first described in: Schmidt, T. T., & Berkemeyer, H. (2018). The Altered States Database: Psychometric Data of Altered States of Consciousness. In Front. Psychol. and an upgrade to cohere to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) 2020 standards has been r
<b>Objectives:</b> To examine perceived risk of harm from weekly cannabis use among reproductive-aged women with disabilities. <b>Methods:</b> Using data from the 2021 National Survey on Drug Use and Health, we assessed perceived risk of harm associated with weekly cannabis use among women of reproductive age by disability status. Disabilities included sensory, cognitive, and those related to daily activities. Logistic regression was employed to examine correlates of risk perception associated w
Violence, alcohol use, substance use and poor mental health have been linked with increased HIV acquisition risk, and genital inflammation enhances HIV susceptibility. We examined whether past 6 month experience of these exposures was associated with increased genital inflammation, thereby providing a biological link between these exposures and HIV acquisition risk. The Maisha Fiti study was a longitudinal mixed-methods study of female sex workers in Nairobi, Kenya. Behavioural-biological survey
Dysmenorrhea, or painful uterine contractions during menstruation in women, is a common condition. It may affect up to 90% of patients in a doctor's office. Depending on the severity of symptoms, it may cause discomfort or prevent normal functioning in everyday life. Some women do not realize that this is not a normal symptom during menstruation. Unfortunately, lack of exercise, smoking, or drinking alcohol only increases the symptoms. A medical history and physical examination of the patient ar
<b>Aim:</b> We aimed to understand experiences with opioids and cannabis for post-treatment cancer survivors. <b>Patients & methods:</b> We conducted seven focus groups among head and neck and lung cancer survivors, using standard qualitative methodology to explore themes around 1) post-treatment pain and 2) utilization, perceived benefits and perceived harms of cannabis and opioids. <b>Results & conclusion:</b> Survivors (N = 25) experienced addiction fears, stigma and access challenges for bot
Peer-reviewed industrial hemp research by Afifa Adiba; Shawn S. Sidhu; Deepika Shaligram; Manal Khan; Zheala Qayyum published in Advances in Psychiatry and Behavioral Health (2023).
The coronavirus disease 2019 (COVID-19) pandemic has had widespread impacts on mental health and substance use. Increases in cannabis use have been documented in the United States, but little is known about how other substance use has changed among people who use cannabis. We sought to examine changes in alcohol, tobacco, opioid, and stimulant use during COVID-19 and explore how these changes relate to patterns of cannabis use. Data were obtained from a web-based survey of adults in the United S
BACKGROUND: Banana peel (Musa balbisiana Colla) already has a diverse variety of nutritional benefits, but its perishable nature necessitates additional food processing, one of which is banana peel floss. AIM: The objective of this study was to examine the antidepressant effects of banana peel floss in experimental animals subjected to chronic mild stress (CMS) for 6 weeks. METHODS: Animals were randomly assigned into five groups. The first group was fed a control diet without CMS as a negative
<b>Background:</b> Over the past decade, there has been increased utilization of medical cannabis (MC) in the United States. Few studies have described sociodemographic and clinical factors associated with MC use after certification and more specifically, factors associated with use of MC products with different cannabinoid profiles. <b>Methods:</b> We conducted a longitudinal cohort study of adults (<i>N</i>=225) with chronic or severe pain on opioids who were newly certified for MC in New York
In patients with chronic neck/back pain, CBD and Δ9-THC are well tolerated and doses of 1.0 mL bd and 1.5 mL bd showed clinically significant reductions in pain compared to baseline pain scores.
The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Prenatal exposures, including substances of abuse, impact fetal development and have effects across the life course. During the development of the HBCD Study, the Pregnancy Exposures, Including Substances Workgroup (WG-PRG) was charged with characteri
Peer-reviewed industrial hemp research by Luis Alberto Henríquez‐Hernández; Ignacio García‐Serrano; Domingo Jesús Quintana Hernández; Jaime Rojas‐Hernández; Elisa Hernández‐Álvarez; Manuel Zumbado; Tobías Fernández‐Borkel; Lucas F. Borkel published in Veterinary Research Communications (2024).
Recently, research is emerging highlighting the potential of cannabinoids' beneficial effects related to anxiety, mood, and sleep disorders as well as pointing to an increased use of cannabinoid-based medicines since COVID-19 was declared a pandemic. The objective of this research is 3 fold: i) to evaluate the relationship of the clinical delivery of cannabinoid-based medicine for anxiety, depression and sleep scores by utilizing machine learning specifically rough set methods; ii) to discover p
Cannabis is the illicit drug most commonly used worldwide, and its consumption can both induce psychiatric symptoms in otherwise healthy subjects and unmask a florid psychotic picture in patients with a prior psychotic risk. Previous studies suggest that chronic and long-term cannabis exposure may exert significant negative effects in brain areas enriched with cannabinoid receptors. However, whether brain alterations determined by cannabis dependency will lead to a clinically significant phenoty
Cannabis use disorder (CUD) is a growing public health concern, with rising prevalence and significant impact on individuals across age groups. This systematic review examined pharmacological and psychosocial interventions for CUD among adolescents, young adults, transitioning adults, and older adults. Database searches were conducted for randomized controlled trials of CUD interventions reporting outcomes such as cannabis use, abstinence, withdrawal symptoms, and treatment retention. In total,
E-cigarette use has been marketed as a safer alternative to traditional cigarettes, as a means of smoking cessation, and are used at a higher rate than the general population in people with HIV (PWH). Early growth receptor 2 (EGR2) and Activity-Regulated Cytoskeleton-Associated Protein (ARC) have a role in addiction, synaptic plasticity, inflammation, and neurodegeneration. This study showed that 10 days of exposure to e-cigarette vapor altered gene expression in the brains of 6-month-old, male,
Tau protein is essential for the structural stability of neurons, particularly through its role in microtubule assembly and axonal transport. However, when abnormally hyperphosphorylated or cleaved, Tau can aggregate into insoluble forms that disrupt neuronal function, contributing to the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD). Emerging evidence suggests that similar Tau-related alterations may occur in individuals with chronic exposure to psychoactive substa
The placebo response has a substantial impact on treatment outcome. However, data regarding mediators of the placebo response in children with autism spectrum disorder (ASD) are sparse. This retrospective study investigated possible mediators of the placebo response among participants of a placebo-controlled trial of cannabinoid treatment for behavioral problems in children with ASD (CBA trial, age 5-21 years). We used a specifically designed questionnaire to explore possible mediators of the pl
ZUSAMMENFASSUNG Cannabinoidkonsum ist mit einem erhöhten Risiko für zahlreiche akute Erkrankungen assoziiert. Die bedeutsamsten akuten psychiatrischen Störungen durch Cannabinoidkonsum sind Intoxikationen. Diese können sich als Delir oder akute Psychose präsentieren. Cannabinoidkonsum erhöht insbesondere bei Adoleszenten das Risiko für Suizidalität und selbstverletzende Verhaltensweisen. Gelegentlich können Cannabinoidentzugssyndrome eine akute Therapie erfordern. Chronischer Cannabinoidkonsum k
These findings point to the potential need for a public health approach to the management of people misusing cannabis. However, there is a gross under-recording of cannabis use in GP records, as seen by the prevalence of recorded cannabis exposure substantially lower than self-reported survey records.
<b>Rationale:</b> The endocannabinoid system is known to be involved in learning, memory, emotional processing and regulation of personality patterns. Here we assessed the endocannabinoid profile in the brains of mice with strong characteristics of social dominance and submissiveness. <b>Methods:</b> A lipidomics approach was employed to assess the endocannabinoidome in the brains of Dominant (Dom) and Submissive (Sub) mice. The endocannabinoid showing the greatest difference in concentration in
Chronic, low-grade inflammation is a key contributor to the development of numerous non-communicable diseases (NCDs), including cardiovascular, metabolic, and neurodegenerative disorders. Conventional anti-inflammatory drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids, often present safety concerns with prolonged use, highlighting the need for safer, multi-targeted therapeutic options. Iridoids, a class of monoterpenoid compounds abundant in several medicinal plant